Medical Tests Required to Apply for U.S. Visas in 2025

Applying for a U.S. visa in 2025? The medical examination is a make-or-break step, and ignorance of the current rules isn’t an excuse. Whether you’re seeking an immigrant Green Card or a non-immigrant visa, the requirements demand careful attention.

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We’ve broken down the complex medical tests, essential vaccinations (and the latest updates!), and crucial procedures you must follow. Get ready to navigate the process like a pro and ensure your health check is a green light, not a roadblock, on your path to the U.S. Read on for the definitive guide.

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Medical Tests for Immigrant Visa Applicants (Green Card)

All applicants for U.S. immigrant visas must complete a mandatory medical examination through an embassy-approved panel physician as per following new requirements:

Test/RequirementWho Must Take ItDetails
Medical History ReviewAll applicantsPast illnesses, hospitalizations, mental health, substance use
Physical ExaminationAll applicantsHeart, lungs, abdomen, skin, ears, eyes, throat, lymph nodes
Tuberculosis (TB) ScreeningApplicants aged 2 and olderInterferon Gamma Release Assay (IGRA) blood test; chest X-ray if positive
Syphilis TestApplicants aged 15 and olderBlood test
Gonorrhea TestApplicants aged 18 to 24Urine test
Vaccination VerificationAll applicantsProof of vaccination against multiple diseases (see below)
Mental Health EvaluationCase-by-case basisAssessment if posing threat to self or others

List of Required Vaccinations for U.S. Immigration (2025)

Vaccination RequiredNotes
Measles, Mumps, RubellaMandatory
PolioMandatory
Tetanus, Diphtheria, PertussisMandatory
Hepatitis BMandatory
Varicella (Chickenpox)Mandatory
Seasonal InfluenzaRequired during flu season
Meningococcal, Pneumococcal, Rotavirus, HibAs applicable for age groups

Important Update:
As of January 20, 2025, COVID-19 vaccination is no longer mandatory for U.S. immigration medical exams. (Source: USCIS)

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Medical Test Requirements for Non-Immigrant Visa Applicants

Most non-immigrant visa applicants (tourists, students, workers) do not need a medical examination.

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However, a medical test may be required if:

Condition Requiring a Medical ExamAdditional Tests
Known public health riskTB screening, physical exam
History of drug or alcohol abuseDrug and alcohol screening
Requested by consular officerBlood tests, TB screening, physical exam

Medical Examination Documentation

Document/RequirementPurposeImportant Notes
Form I-693For applicants adjusting status inside the U.S.Forms signed after Nov 1, 2023, do not expire
Sealed Medical ReportFor applicants applying outside the U.S.Submit sealed envelope at visa interview; do not open it yourself

When to Schedule Your Medical Exam?

StepTiming Recommendation
Visa Interview ScheduledThen immediately book your medical exam
Medical Exam CompletionAt least 5 working days before the visa interview

Tip: Always use an approved panel physician listed by the U.S. Embassy or Consulate where you are applying.

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References

DATE . Apr/29/2025

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